Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together.As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel. Such a supermodel of marginals of Bayesian networks, defined only by conditional independences, and termed the ordinary Markov model, was studied at length in (Evans and Richardson, 2014).In this paper, we show that special mixed graphs which we call segregated graphs can be associated, via a Markov property, with supermodels of a marginal of chain graphs defined only by conditional independences. Special features of segregated graphs imply the existence of a very natural factorization for these supermodels, and imply many existing results on the chain graph model, and ordinary Markov model carry over. Our results suggest that segregated graphs define an analogue of the ordinary Markov model for marginals of chain graph models.
Predicated on the increasing abundance of electronic health records, we investigate the problem of inferring individualized treatment effects using observational data. Stemming from the potential outcomes model, we propose a novel multi-task learning framework in which factual and counterfactual outcomes are modeled as the outputs of a function in a vector-valued reproducing kernel Hilbert space (vvRKHS). We develop a nonparametric Bayesian method for learning the treatment effects using a multi-task Gaussian process (GP) with a linear coregionalization kernel as a prior over the vvRKHS. The Bayesian approach allows us to compute individualized measures of confidence in our estimates via pointwise credible intervals, which are crucial for realizing the full potential of precision medicine. The impact of selection bias is alleviated via a risk-based empirical Bayes method for adapting the multi-task GP prior, which jointly minimizes the empirical error in factual outcomes and the uncertainty in (unobserved) counterfactual outcomes. We conduct experiments on observational datasets for an interventional social program applied to premature infants, and a left ventricular assist device applied to cardiac patients wait-listed for a heart transplant. In both experiments, we show that our method significantly outperforms the state-of-the-art.
Artificial intelligence is enabling many scientific breakthroughs, especially in fields of study that generate high volumes of complex data such as neuroscience. As impossible as it may seem, neuroscientists are making strides in decoding neural activity into speech using artificial neural networks. Yesterday, the neuroscience team of Gopala K. Anumanchipalli, Josh Chartier, and Edward F. Chang of University of California San Francisco (UCSF) published in Nature their study using artificial intelligence and a state-of-the-art brain-machine interface to produce synthetic speech from brain recordings. The concept is relatively straightforward--record the brain activity and audio of participants while they are reading aloud in order to create a system that decodes brain signals for vocal tract movements, then synthesize speech from the decoded movements. The execution of the concept required sophisticated finessing of cutting-edge AI techniques and tools.
IBM said on Thursday it will spend $240 million over the next decade to fund a new artificial intelligence research lab at the Massachusetts Institute of Technology. The resulting MIT–IBM Watson AI Lab will focus on a handful of key AI areas including the development of new "deep learning" algorithms. Deep learning is a subset of AI that aims to bring human-like learning capabilities to computers so they can operate more autonomously. The Cambridge, Mass.-based lab will be led by Dario Gil, vice president of AI for IBM Research and Anantha Chandrakasan, dean of MIT's engineering school. It will draw upon about 100 researchers from IBM (ibm) itself and the university.
As probabilistic systems gain popularity and are coming into wider use, the need for a mechanism that explains the system's findings and recommendations becomes more critical. The system will also need a mechanism for ordering competing explanations. We examine two representative approaches to explanation in the literature - one due to G\"ardenfors and one due to Pearl - and show that both suffer from significant problems. We propose an approach to defining a notion of "better explanation" that combines some of the features of both together with more recent work by Pearl and others on causality.