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### Generalizing Distance Covariance to Measure and Test Multivariate Mutual Dependence

We propose three measures of mutual dependence between multiple random vectors. All the measures are zero if and only if the random vectors are mutually independent. The first measure generalizes distance covariance from pairwise dependence to mutual dependence, while the other two measures are sums of squared distance covariance. All the measures share similar properties and asymptotic distributions to distance covariance, and capture non-linear and non-monotone mutual dependence between the random vectors. Inspired by complete and incomplete V-statistics, we define the empirical measures and simplified empirical measures as a trade-off between the complexity and power when testing mutual independence. Implementation of the tests is demonstrated by both simulation results and real data examples.

### Kernel Measures of Conditional Dependence

We propose a new measure of conditional dependence of random variables, based on normalized cross-covariance operators on reproducing kernel Hilbert spaces. Unlike previous kernel dependence measures, the proposed criterion does not depend onthe choice of kernel in the limit of infinite data, for a wide class of kernels. Atthe same time, it has a straightforward empirical estimate with good convergence behaviour. We discuss the theoretical properties of the measure, and demonstrate its application in experiments.

### Sensitivity Maps of the Hilbert-Schmidt Independence Criterion

Kernel dependence measures yield accurate estimates of nonlinear relations between random variables, and they are also endorsed with solid theoretical properties and convergence rates. Besides, the empirical estimates are easy to compute in closed form just involving linear algebra operations. However, they are hampered by two important problems: the high computational cost involved, as two kernel matrices of the sample size have to be computed and stored, and the interpretability of the measure, which remains hidden behind the implicit feature map. We here address these two issues. We introduce the Sensitivity Maps (SMs) for the Hilbert-Schmidt independence criterion (HSIC). Sensitivity maps allow us to explicitly analyze and visualize the relative relevance of both examples and features on the dependence measure. We also present the randomized HSIC (RHSIC) and its corresponding sensitivity maps to cope with large scale problems. We build upon the framework of random features and the Bochner's theorem to approximate the involved kernels in the canonical HSIC. The power of the RHSIC measure scales favourably with the number of samples, and it approximates HSIC and the sensitivity maps efficiently. Convergence bounds of both the measure and the sensitivity map are also provided. Our proposal is illustrated in synthetic examples, and challenging real problems of dependence estimation, feature selection, and causal inference from empirical data.

### A Distance Covariance-based Kernel for Nonlinear Causal Clustering in Heterogeneous Populations

We consider the problem of causal structure learning in the setting of heterogeneous populations, i.e., populations in which a single causal structure does not adequately represent all population members, as is common in biological and social sciences. To this end, we introduce a distance covariance-based kernel designed specifically to measure the similarity between the underlying nonlinear causal structures of different samples. This kernel enables us to perform clustering to identify the homogeneous subpopulations. Indeed, we prove the corresponding feature map is a statistically consistent estimator of nonlinear independence structure, rendering the kernel itself a statistical test for the hypothesis that sets of samples come from different generating causal structures. We can then use existing methods to learn a causal structure for each of these subpopulations. We demonstrate using our kernel for causal clustering with an application in genetics, allowing us to reason about the latent transcription factor networks regulating measured gene expression levels.

### High-Dimensional Covariance Decomposition into Sparse Markov and Independence Domains

In this paper, we present a novel framework incorporating a combination of sparse models in different domains. We posit the observed data as generated from a linear combination of a sparse Gaussian Markov model (with a sparse precision matrix) and a sparse Gaussian independence model (with a sparse covariance matrix). We provide efficient methods for decomposition of the data into two domains, \viz Markov and independence domains. We characterize a set of sufficient conditions for identifiability and model consistency. Our decomposition method is based on a simple modification of the popular $\ell_1$-penalized maximum-likelihood estimator ($\ell_1$-MLE). We establish that our estimator is consistent in both the domains, i.e., it successfully recovers the supports of both Markov and independence models, when the number of samples $n$ scales as $n = \Omega(d^2 \log p)$, where $p$ is the number of variables and $d$ is the maximum node degree in the Markov model. Our conditions for recovery are comparable to those of $\ell_1$-MLE for consistent estimation of a sparse Markov model, and thus, we guarantee successful high-dimensional estimation of a richer class of models under comparable conditions. Our experiments validate these results and also demonstrate that our models have better inference accuracy under simple algorithms such as loopy belief propagation.