[Editors' Choice] Polarity reversal during tissue remodeling


The epithelial-mesenchymal transition occurs when epithelial cells lose apicobasal polarity and cell-cell contacts and migrate into surrounding tissues as mesenchymal cells. Migration is crucial for gastrulation, neural tube formation, and cancer metastasis. However, the mechanisms underlying loss of polarity and cell movement are poorly understood. The change in cell organization results in the transition from apicobasal polarity to front-rear polarity that precedes cell migration. Micropatterned cell culture showed that the mechanism is cell-intrinsic and governed by microtubule reorganization but is not influenced by neighboring cells.

Sentiment Classification Using the Meaning of Words

AAAI Conferences

Sentiment Classification (SC) is about assigning a positive, negative or neutral label to a piece of text based on its overall opinion. This paper describes our in-progress work on extracting the meaning of words for SC. In particular, we investigate the utility of sense-level polarity information for SC. We first show that methods based on common classification features are not robust and their performance varies widely across different domains. We then show that sense-level polarity information features can significantly improve the performance of SC. We use datasets in different domains to study the robustness of the designated features. Our preliminary results show that the most common sense of the words result in the most robust results across different domains. In addition our observation shows that the sense-level polarity information is useful for producing a set of high-quality seed words which can be used for further improvement of SC task.

A Simple Approach to Multilingual Polarity Classification in Twitter

arXiv.org Machine Learning

Recently, sentiment analysis has received a lot of attention due to the interest in mining opinions of social media users. Sentiment analysis consists in determining the polarity of a given text, i.e., its degree of positiveness or negativeness. Traditionally, Sentiment Analysis algorithms have been tailored to a specific language given the complexity of having a number of lexical variations and errors introduced by the people generating content. In this contribution, our aim is to provide a simple to implement and easy to use multilingual framework, that can serve as a baseline for sentiment analysis contests, and as starting point to build new sentiment analysis systems. We compare our approach in eight different languages, three of them have important international contests, namely, SemEval (English), TASS (Spanish), and SENTIPOLC (Italian). Within the competitions our approach reaches from medium to high positions in the rankings; whereas in the remaining languages our approach outperforms the reported results.

Weakly Supervised Induction of Affective Events by Optimizing Semantic Consistency

AAAI Conferences

To understand narrative text, we must comprehend how people are affected by the events that they experience. For example, readers understand that graduating from college is a positive event (achievement) but being fired from one's job is a negative event (problem). NLP researchers have developed effective tools for recognizing explicit sentiments, but affective events are more difficult to recognize because the polarity is often implicit and can depend on both a predicate and its arguments. Our research investigates the prevalence of affective events in a personal story corpus, and introduces a weakly supervised method for large scale induction of affective events. We present an iterative learning framework that constructs a graph with nodes representing events and initializes their affective polarities with sentiment analysis tools as weak supervision. The events are then linked based on three types of semantic relations: (1) semantic similarity, (2) semantic opposition, and (3) shared components. The learning algorithm iteratively refines the polarity values by optimizing semantic consistency across all events in the graph. Our model learns over 100,000 affective events and identifies their polarities more accurately than other methods.

Modeling Polarizing Topics: When Do Different Political Communities Respond Differently to the Same News?

AAAI Conferences

Political discourse in the United States is getting increasingly polarized. This polarization frequently causes different communities to react very differently to the same news events. Political blogs as a form of social media provide an unique insight into this phenomenon. We present a multitarget, semisupervised latent variable model, MCR-LDA to model this process by analyzing political blogs posts and their comment sections from different political communities jointly to predict the degree of polarization that news topics cause. Inspecting the model after inference reveals topics and the degree to which it triggers polarization. In this approach, community responses to news topics are observed using sentiment polarity and comment volume which serves as a proxy for the level of interest in the topic. In this context, we also present computational methods to assign sentiment polarity to the comments which serve as targets for latent variable models that predict the polarity based on the topics in the blog content. Our results show that the joint modeling of communities with different political beliefs using MCR-LDA does not sacrifice accuracy in sentiment polarity prediction when compared to approaches that are tailored to specific communities and additionally provides a view of the polarization in responses from the different communities.