We introduce the Gamma-Exponential Process (GEP), a prior over a large family ofcontinuous time stochastic processes. A hierarchical version of this prior (HGEP; the Hierarchical GEP) yields a useful model for analyzing complex time series. Models based on HGEPs display many attractive properties: conjugacy, exchangeability and closed-form predictive distribution for the waiting times, and exact Gibbs updates for the time scale parameters. After establishing these properties, weshow how posterior inference can be carried efficiently using Particle MCMC methods . This yields a MCMC algorithm that can resample entire sequences atomicallywhile avoiding the complications of introducing slice and stick auxiliary variables of the beam sampler . We applied our model to the problem of estimating the disease progression in multiple sclerosis , and to RNA evolutionary modeling. In both domains, we found that our model outperformed the standard rate matrix estimation approach.
Social dynamics is concerned primarily with interactions among individuals and the resulting group behaviors, modeling the temporal evolution of social systems via the interactions of individuals within these systems. In particular, the availability of large-scale data from social networks and sensor networks offers an unprecedented opportunity to predict state-changing events at the individual level. Examples of such events include disease transmission, opinion transition in elections, and rumor propagation. Unlike previous research focusing on the collective effects of social systems, this study makes efficient inferences at the individual level. In order to cope with dynamic interactions among a large number of individuals, we introduce the stochastic kinetic model to capture adaptive transition probabilities and propose an efficient variational inference algorithm the complexity of which grows linearly --- rather than exponentially --- with the number of individuals. To validate this method, we have performed epidemic-dynamics experiments on wireless sensor network data collected from more than ten thousand people over three years. The proposed algorithm was used to track disease transmission and predict the probability of infection for each individual. Our results demonstrate that this method is more efficient than sampling while nonetheless achieving high accuracy.
Bayesian networks are a popular representation of asymmetric (for example causal) relationships between random variables. Markov random fields (MRFs) are a complementary model of symmetric relationships used in computer vision, spatial modeling, and social and gene expression networks. A chain graph model under the Lauritzen-Wermuth-Frydenberg interpretation (hereafter a chain graph model) generalizes both Bayesian networks and MRFs, and can represent asymmetric and symmetric relationships together.As in other graphical models, the set of marginals from distributions in a chain graph model induced by the presence of hidden variables forms a complex model. One recent approach to the study of marginal graphical models is to consider a well-behaved supermodel. Such a supermodel of marginals of Bayesian networks, defined only by conditional independences, and termed the ordinary Markov model, was studied at length in (Evans and Richardson, 2014).In this paper, we show that special mixed graphs which we call segregated graphs can be associated, via a Markov property, with supermodels of a marginal of chain graphs defined only by conditional independences. Special features of segregated graphs imply the existence of a very natural factorization for these supermodels, and imply many existing results on the chain graph model, and ordinary Markov model carry over. Our results suggest that segregated graphs define an analogue of the ordinary Markov model for marginals of chain graph models.
We propose a new interpretation of spiking neurons as Bayesian integrators accumulatingevidence over time about events in the external world or the body, and communicating to other neurons their certainties about these events. In this model, spikes signal the occurrence of new information, i.e.what cannot be predicted from the past activity. As a result, firing statistics are close to Poisson, albeit providing a deterministic representation ofprobabilities. We proceed to develop a theory of Bayesian inference in spiking neural networks, recurrent interactions implementing avariant of belief propagation. Many perceptual and motor tasks performed by the central nervous system are probabilistic, andcan be described in a Bayesian framework [4, 3].