How is machine learning advancing cancer research?


Every day, each of the trillions of cells in the human body receives over 10,000 DNA lesions, which if unrepaired can lead to mutations and diseases, such as cancer. Luckily, we have complex machinery that detects and repairs DNA lesions; however, there is a lack of tools to study this machinery. Now, researchers from the Spanish National Cancer Research Center (CNIO; Madrid, Spain) and Massachusetts General Hospital (MGH; MA, USA) have used machine learning and high-throughput microscopy to visualize DNA repair machinery and identify new repair proteins, which could aid the development of novel cancer therapies.