Naked droplets for culturing cells


Cellular behavior and interactions are best modeled in vitro using 3D constructs because they closely mimic in vivo environments. Both scaffold and nonscaffold techniques have been developed, but these methods can be time consuming, expensive, or hard to do reproducibly. Chen et al. show that low-volume droplets, placed inside superhydrophobic coated plates, create a medium in which cells can float freely and rapidly grow into spheroids.